$ 0 0 Seven-time Grand Slam champion VenusWilliams fell out of the AustralianOpen at the first hurdle after a marathon clash with Russian 22nd seed Ekaterina Makarova on Monday. The former world number one was unseeded in Melbourne despite playing 11 events last year and making three semifinals, and she looked on course for victory after winning the first set. But a series of unforced errors and failure to convert crucial break points cost her dearly and she was sent packing 2-6, 6-4, 6-4 after a nearly two-and-half-hour epic in blazing hot conditions. Williams hasn't won a Grand Slam since Wimbledon in 2008 and is without a title since Luxembourg in October 2012, but she made the final of the warm-up Auckland International, losing a three-set final to Ana Ivanovic. It put her in good stead for Melbourne but after being diagnosed with energy-sapping Sjogren's Syndrome in 2011, and adopting a raw foods diet to ease her symptoms, she pulled out of last week's Hobart International to rest. It appeared to pay dividends as a fresh Williams got an early break to go 2-0 up before the Russian immediately broke back. Williams is seeking to stay in touch with the game's elite after two years marred by battling illness and injury, and her trademark booming serve was firing. She was also returning well and sent some sizzling winners off her backhand to secure two more breaks and take the first set 6-2 in 31 minutes.